Pings
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1 Answer 0 Votes
What validated tools or frameworks exist for detecting and mitigating AI/LLM hallucinations in systematic review methodology in resource constrained settings ?
I have published survey based research on AI hallucination awareness among early career medical researchers in Pakistan (medRxiv preprint live). I am seeking expert input on validated detection frameworks or mitigation strategies specifically applicable to systematic review workflows in low and middle income country research contexts where verification infrastructure is limited.
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1 Answer 0 Votes
What are the most reliable surrogate markers for early diabetic nephropathy progression in primary care settings without access to advanced biomarker panels?
I am an internal medicine physician conducting primary care based research on diabetic nephropathy in Pakistan. In our setting, advanced biomarkers such as KIM-1, NGAL and cystatin C are unavailable. I am seeking expert consensus on which routinely available markers including urine ACR, eGFR trajectory, blood pressure patterns, and HbA1c best predict early CKD progression in T2DM patients in resource limited environment.
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0 Answers 0 Votes
What is the current evidence for GLP1 receptor agonists as disease modifying agents in multiple sclerosis, beyond metabolic and weight effects?
I am conducting a PROSPERO registered systematic review and meta analysis on GLP-1 receptor agonists in multiple sclerosis (CRD420261385854). I am seeking expert perspectives on whether current preclinical and clinical evidence supports a disease modifying mechanism or whether observed benefits are secondary to metabolic and weight improvements.
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2 Answers 0 Votes
How does friccohesity chemistry act as global physicochemical property with quantum mechanical activity to nanoformulate the smart cosmetics, syrups, supplements, lubricants, antiwrinkle creams ?
Currently, the friccohesity measured using survismeter has emerged as global physicochemical property of smart research methodologies for nanoformulations to bring all the ingredients in a most aligned coordination for generating the extra mileage of each ingredient for applications.
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4 Answers 0 Votes
Which impact has Bempedoic Acid on atherosclrosis plaque stability ?
Mechanism of action
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7 Answers 3 Votes
For a change in the peer-reveiwing as an urgent need?
With an increasing number of Journal and other publication, the review by peer started to be difficult and very often nonqualified reviewers are solicited. Very often now the Journal send us a list that ressemble the directory a. This is a problem since many of the persons listed here do not have even a record over 10 and there are supposed to review works they don't know, and they are not qualified. I would like to start a huge discussion that can be sent to the main Journal to change the...
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4 Answers 1 Vote
Should Impact Factor be the standard for judging how sound a journal is?
Impact Factor is about citations and not necessarily quality
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6 Answers 2 Votes
When the policy exists to share postprints freely on personal sites, why do researchers often refrain from doing so, and what incentives or constraints drive that hesitation?
There has been extensive discussion about the funding model for research publications. Large publishing houses do not fund research themselves; instead, they charge substantial subscription fees or open-access publishing fees. Keeping articles behind paywalls can impede open science and broad access to knowledge. Nevertheless, many publishers grant authors the right to share postprints of their papers immediately on their non-commercial personal blogs or websites. Despite this permission,...
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9 Answers 0 Votes
What is the most important part of a scientific article? Let's approach this seriously!
I read a question asking what is the most important part of a scientific article. As far as I can see, we have all gone crazy. The most significant part of a scientific article is… simply ALL OF IT. By the way, nobody has commented on the REFERENCES. Or is a copy-paste enough?
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Answer Accepted 2 Answers 0 Votes
What can be expected from the development of preventive vaccines for non virally-induced cancers?
The introduction of prophylactic vaccines for virally-induced cancers (primarily HBV and HPV) has achieved a tremendous impact on disease related deaths. This has, in time, raised interest in developing vaccines to intercept pre-cancerous cells based on their expression of aberrant self-antigens (e.g. hypoglycosilated MUC1 in colon, lung and breast carcinomas). As of 2024, a number of phase I clinical studies have been ongoing in the USA, for both primary prevention and early cancer...
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