Pings
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2 Answers 0 Votes
How to examine for power of grip in a patient with weakness?
When we do clinical examination for weakness, power is ascertained by MRC grading. However, for grip, MRC grading cannot be used. Is there any method to examine hand grip power other than using dynamometer
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6 Answers 4 Votes
How might AI-assisted peer review tools reshape scientific publishing, and what safeguards should be implemented to maintain review quality while addressing the increasing volume of submissions?
The peer-reviewing process is being faced with ever-growing challenges as submission rates are still rising exponentially in all areas. Journal editors are faced with the challenge of getting capable reviewers who are ready to volunteer their time, with a result being delays in reviewing, reviewer exhaustion, and worse, compromised quality. Meanwhile, AI technologies are accelerating their ability to review scientific manuscripts for methodology, statistical fitting, plagiarism screenings,...
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Answer Accepted 3 Answers 2 Votes
Does insulin therapy activate the anti-aging gene Sirtuin 1 that is critical for the prevention of insulin iresistance?
The anti-aging gene Sirtuin 1 is important to the prevention of accelerated aging and diabetes. Sirtuin 1 activators are critical to the treatment of diabetes, cardiovascular disease and Alzheimer’s disease. Sirtuin 1 inhibitors cause insulin resistance and reduce plasma Sirtuin 1 levels. Insulin therapy is critical to the treatment of diabetes and plasma Sirtuin 1 levels need to be measured with relevance to the treatment and prevention of insulin resistance. RELEVANT REFERENCES: 1. ...
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3 Answers 0 Votes
What threshold of urinary cadmium (Cd-U) is currently considered indicative of early renal tubular dysfunction in exposed adult populations?
I am conducting a study on chronic environmental cadmium exposure and its nephrotoxic effects, particularly focusing on early biomarkers of renal tubular damage. Several sources suggest 2 µg/g creatinine as a reference point, but variability exists depending on population, sex, and co-exposure. Could experts clarify which threshold (e.g. 1 µg/g, 2 µg/g, or 5 µg/g creatinine) is most reliable or currently used in risk assessments and clinical practice?
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Answer Accepted 7 Answers 2 Votes
Do you think general physicians or medical doctors might be redundant when AGI is fully developed?
This is a burning topic in medical or clinicians' circles globally as it might have the potential to shake up the medical profession due to the concerted efforts by AI enthusiasts by questioning the relevance of the doctors e.g. general physicians if not all (e.g. medial surgeons or specialists). This may be a challenge for the future healthcare planners and might need a thorough debate. The following reference might give a glimpse and assist while answering for my ping question. Kazzazi F....
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Answer Accepted 1 Answer 0 Votes
I am conducting a field experiment using a randomized complete block design. The layout includes 5 blocks, each of equal land area. Within each block, there are 5 plots, and each plot receives a diffe
I am conducting a field experiment using a randomized complete block design. The layout includes 5 blocks, each of equal land area. Within each block, there are 5 plots, and each plot receives a different single treatment. These 5 treatments are repeated across all blocks, so each treatment is replicated five times in total—once per block. My question concerns sample collection for a single treatment. What is the scientifically valid and recommended method for collecting samples and...
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7 Answers 4 Votes
How do you justify (or would you justify) a new research study to ensure it doesn’t unnecessarily duplicate previous work or repeat past methodological mistakes?
I’m currently working on a PhD thesis focused on Evidence-Based Research (EBR), particularly on how researchers use (or fail to use) prior evidence (similar studies), to justify and design new research. I’d love to hear real-world experiences, whether from preparing research proposals or evaluating them. Do you use any structured or unstructured method to be aware of all relevant prior research? How do you support your judgments (e.g., demonstrating that no prior studies exist, or that...
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1 Answer 0 Votes
Which impact has Bempedoic Acid on atherosclrosis plaque stability ?
Mechanism of action
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7 Answers 3 Votes
What is the most important research material in protein bioinformatics? 1. Protein sequence 2. Protein structure 3. Protein-related Software 4. A high-speed computer
A protein's sequence contains its intrinsic properties as a code. Nobel laureate scientist, C. B. Anfinsen proved it through experiments. Unlike sequence, since structures are man-made and obtained under different laboratory conditions, they may contain human error. Further, unlike nucleic acid, to date, the protein-folding code is unknown. So, in my opinion the study of protein sequence is primary. It is better if one can include structure study with it. But little can be said about this...
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23 Answers 54 Votes
For respiratory viruses, should folks wear masks in public a) always, b) if they are or may be infected, or c) if they are afraid of getting infected? Are masks a) protection, or b) social signals?
Since 2020, the public has thought of masks as having a protective purpose, and many rebel at the inconvenience, rationalizing that “they do a poor job of protecting.” Is the current epidemic a good opportunity for government and medicine to teach the folks about the more important virtues of using masks to convey information?
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